Symptoms can include high fever, excessive sweating, rigid muscles, confusion, or changes in breathing, heartbeat, or blood pressure. If you become very ill with these symptoms, call 911 right away. Long-term use of antipsychotic drugs can also increase the risk of weight gain and diabetes, so it is advised to consult with your doctor about the ways you can prevent weight gain and maintain a healthy lifestyle. Your doctor will likely monitor your blood sugar and cholesterol, to ensure they remain at healthy levels 1.
If you stop quetiapine suddenly, it could lead to withdrawal symptoms, such as nausea, vomiting, or difficulty sleeping. Do not stop taking quetiapine without talking with your healthcare provider. Talk to your healthcare provider about how to stop quetiapine to reduce the risk of withdrawal reactions.
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It is very important that your doctor check your or your child’s progress at regular visits to make sure this medicine is working properly. Blood and urine tests may be needed to check for unwanted effects. You may also need to have your eyes tested on a regular basis.
Symptoms of Overdose
Avoid getting up too fast from a sitting or lying position, or you may feel dizzy. Avoid driving or hazardous activity until you know how quetiapine will affect you. Dizziness or drowsiness can cause falls, accidents, quetiapine seroquel: uses side effects or severe injuries. It may be harder for you to get pregnant while you are using quetiapine.
What other drugs will affect quetiapine?
If you are pregnant or planning to become pregnant, it’s important to discuss the potential risks and benefits of continuing Quetiapine with your healthcare provider. They can help you make an informed decision based on your individual circumstances. A major depressive episode may be the initial presentation of bipolar disorder. It is generally believed (though not established in controlled trials) that treating such an episode with an antidepressant alone may increase the likelihood of precipitation of a mixed/manic episode in patients at risk for bipolar disorder.
Drug Summary
Increased doses of SEROQUEL up to 5 fold may be required to maintain control of symptoms of schizophrenia in patients receiving quetiapine and phenytoin, or other known potent CYP3A4 inducers see DOSAGE AND ADMINISTRATION and CLINICAL PHARMACOLOGY. When the CYP3A4 inducer is discontinued, the dose of SEROQUEL should be reduced to the original level within 7-14 days see DOSAGE AND ADMINISTRATION. The risks of using SEROQUEL in combination with other drugs have not been extensively evaluated in systematic studies. Given the primary CNS effects of SEROQUEL, caution should be used when it is taken in combination with other centrally acting drugs.
Effect Of Quetiapine On Other Drugs
- Taking antipsychotic medicine in the last 3 months of pregnancy may cause serious problems in the newborn.
- This database includes 677 patients exposed to Seroquel for the treatment of schizophrenia and 393 children and adolescents (10-17 years old) exposed to Seroquel for the treatment of acute bipolar mania.
- Quetiapine can interact with other medications, increasing the risk of side effects or reducing the effectiveness of either drug.
- The efficacy of SEROQUEL in schizophrenia was established in three 6-week trials in adults and one 6-week trial in adolescents (13-17 years).
Risperidone is used to treat schizophrenia and symptoms of bipolar disorder. There is a higher risk of death, stroke, or mini-stroke, also called a transient ischemic attack (TIA), in older adults who take quetiapine or another antipsychotic and have memory loss or psychosis related to dementia. Quetiapine is not approved to treat dementia-related psychosis. Quetiapine may interact with other medicines and supplements.
Does Seroquel (quetiapine) cause addiction or withdrawal symptoms?
Like any drug, certain doses of Seroquel may cause side effects in some people and not in others. It’s approved for certain types of bipolar disorder and schizophrenia. But if you have symptoms that are ongoing or bother you, talk with your doctor or pharmacist.
- For some patients, this medicine can increase thoughts of suicide.
- If you are pregnant, planning to become pregnant, or breastfeeding, discuss with your healthcare provider whether Quetiapine is safe for you.
- As research continues to evolve, staying informed about new findings is essential.
- Seroquel may increase the risk of death in older adults with mental health problems related to dementia.
- Ambien is primarily used to treat insomnia, while Seroquel is used to treat insomnia off-label.
Thyroid follicular cell adenomas may have resulted from chronic stimulation of the thyroid gland by thyroid stimulating hormone (TSH) resulting from enhanced metabolism and clearance of thyroxine by rodent liver. Changes in TSH, thyroxine, and thyroxine clearance consistent with this mechanism were observed in subchronic toxicity studies in rat and mouse and in a 1-year toxicity study in rat; however, the results of these studies were not definitive. The relevance of the increases in thyroid follicular cell adenomas to human risk, through whatever mechanism, is unknown.
These studies did not show an increase in the risk of suicidal thoughts and behavior with antidepressant use in patients over age 24; there was a reduction in risk with antidepressant use in patients aged 65 and older see WARNINGS AND PRECAUTIONS. The adverse event leading to discontinuation in 1% or more of patients on Seroquel and at a greater incidence than placebo was somnolence (2.7% and 0% for placebo). Using this medicine with any of the following medicines may cause an increased risk of certain side effects, but using both drugs may be the best treatment for you. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines. Sometimes it is not safe to use certain medicines at the same time.
